ONU professors author personalized medicine textbook
Three members of the Ohio Northern University Raabe College of Pharmacy, along with a member of the Purdue University faculty, have collaborated to author a textbook titled “Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine.”
Ohio Northern’s David F. Kisor, professor of pharmacokinetics, Jon E. Sprague, dean and professor of pharmacology, Jeffrey N. Talbot, associate professor of pharmacology, and Michael D. Kane, associate professor of bioinformatics and genomics at Purdue, contributed to the textbook, which will be used by pharmacy students and pharmacists.
“Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine” provides a primer for understanding pharmacogenetics (the study of genetic factors that influence how people respond to drug therapy) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, i.e., “personalized medicine.”
“The book is important because it is translational in nature, meaning that it connects the basic science to clinical application,” Kisor said. “We believe this book is the most ‘clinically applicable’ textbook. There are some very good reference and introductory textbooks available, but our book is not intended to be a reference book. It is aimed at bringing the science to the clinical setting in a very practical way.”
Through specific drug examples, the textbook explores how the genetic constitution of an individual may lead to the need for an altered dose or, in some cases, alternative drug therapy. Real-world cases highlight the specific relationships between genetics, drug action and the body’s response as well as adverse drug reactions, altered metabolism and drug efficacy.
Stories Posted This Week
Monday, April 28, 2025
- Anabel R. McBride worked for Ada Exempted Village Schools
- Trash to Treasure STEAM program on May 3
- Student entrepreneurs compete in 2025 Polar Innovation Exchange
- Lifesaving AED installed at One More gym on E. Buckeye
- St. Mark Community Meal is April 30
- Alfes wins Medalist honors at OAC golf championships
- Wilma A. Willeke worked at Ohio Northern
Sunday, April 27, 2025
Saturday, April 26, 2025
Friday, April 25, 2025
Thursday, April 24, 2025
- UPDATED Ada Police Department assists U.S. Marshal's Service with April 21 arrest
- Honda honors Ada Technologies, Inc. for performance
- Meet the 2025 Ada High School Prom court
- Bad Dreams: Health implications
- Bulldog softball run-rules Van Buren
- Bulldog baseball loss to unbeaten Van Buren
- Ada Board of Education to meet May 15
- ONU sports roundup, April 16-22
- Garage Sale season has started on the Icons!
- Ada Gators summer swim registration is open